Neuroscience is a word that is about as intimidating as astrophysics. Most people have no idea what it means, but they’re pretty sure that its definition is over their head. The truth is that neuroscience is simply the study of the brain and nervous system. That’s not to say it’s a simple science, but it’s a science that covers equipment that we all have. With that said, neuroscience gets a bit complex as it draws from “other fields such as chemistry, computer science, engineering, linguistics, mathematics, medicine and allied disciplines, philosophy, physics, and psychology.” (Here’s the Wikipedia article on Neuroscience.) The Society for Neuroscience is a Washington, DC based non-profit member organization for the scientists and physicians who study the brain and nervous system.
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100 years ago today the Titanic sank. It wasn’t the world’s first transportation disaster, nor was it the last, but it’s the one that continues to captivate people. As a kid I was absolutely fascinated by the story of the Titanic–the unsinkable ship that sank. I had a few books on the topic that I read over and over again. I learned about Alvin, the deep sea submersible, and Jason Jr., the underwater robot, and how they were used to explore the Titanic once it was discovered in 1985 (by essentially dragging video cameras just above the ocean floor). The discovery and expeditions were partially done by teams from the Woods Hole Oceanographic Institution, which is a Woods Hole, MA based “non-profit research and higher education facility dedicated to the study of all aspects of marine science and engineering and to the education of marine researchers.” If it has to do with ocean science and exploration, there’s an extremely good chance that the Woods Hole Oceanographic Institution is on top of it.
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Just a few days ago I mentioned that computers are better than humans at math. That’s true for many math operations, but the ultimate combination is a smart human working with a fast computer and great software. MathWorks is a Natick, MA based company that makes this possible, as they are “the leading developer of mathematical computing software for engineers and scientists.” They’ve been around for nearly 30 years, which is a seriously long time in the software business. MathWorks is probably best known for MATLAB, which is “a programming environment for algorithm development, data analysis, visualization, and numeric computation.” It’s used everywhere from research in top universities to designing industrial machines. If advanced math is involved, there’s a good chance that MATLAB will be used.
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One of the most amazing things about the United States is our National Park system (check out National Park Service jobs)–it really shows off how vast and how diverse the country’s natural beauty is. While you’ve probably visited at least one National Park and know of many more, chances are that you’ve never heard of National Marine Sanctuaries. NOAA manages the system of sanctuaries “to conserve, protect, and enhance their biodiversity, ecological integrity and cultural legacy.” The National Marine Sanctuary Foundation is a Silver Spring, MD based non-profit organization that “was created to assist the federally managed National Marine Sanctuary Program with education and outreach programs designed to preserve, protect and promote meaningful opportunities for public interaction with the nation’s marine sanctuaries.”
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“Yo I’m a Raptor doin’ what I can gonna eat everything till the appearance of man. Yo yo yo, see me, I’m living below the soil, I’ll be back but I’m comin’ as oil!” That has to be one of my favorite lines from Mrs. Doubtfire, a movie that I saw dozens of time as a kid. I thought it was funny even though I had no idea what it meant (probably because Robin Williams saying anything is funny). Mrs. Doubtfire was on tv recently, and I saw the scene for the first time in a long time and finally got it. Disappointingly, petroleum doesn’t actually come from dinosaurs, but from decomposed single-celled organisms that existed 10s or 100s of millions of years ago. That means that oil is a non-renewable resource… or at least it used to be. Solazyme is a San Francisco, CA based company that has “pioneered an industrial biotechnology platform that harnesses the prolific oil-producing ability of micro algae.” Yes, they are actually synthesizing real oil that can be refined and used to power things. They feed the algae sugar, so as long you can keep growing sugar (from a variety of sources), you can keep producing oil.
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For the most part illness is an individual problem. You get sick, you go to a doctor if it’s serious enough, and it eventually gets better with or without treatment. But sometimes your illness can be a public health issue. If you get something like influenza or food poisoning, there’s a good chance that information about your illness could help lots of other people stay healthy. At times like these “when new health risks emerge or well-known problems re-emerge, it is public health laboratories that analyze the threat and provide the answers needed to mount an effective response.” The Association of Public Health Laboratories is a non-profit organization based in Silver Spring, MD that “works to strengthen laboratories serving the public’s health in the US and globally.” The organization’s membership spans across all kinds of laboratories ranging from the public health labs mentioned in their name to environmental and agricultural labs. Many are government labs, but there are also corporate and non-profit labs included.
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Last night I started watching Planet Earth and ended up staying awake later than I intended. This morning the same channel was on, and I ended up watching documentaries on Yellowstone. There aren’t many things that I find more fascinating than nature, so it’s easy for me to get caught up in these kinds of shows. It’s also why I think the work of The Nature Conservancy is so important. They’re an international non-profit organization based in Arlington, VA that is “the leading conservation organization working around the world to protect ecologically important lands and waters for nature and people.” The Nature Conservancy was founded in 1951, and since then they have grown their membership to more than 1 million people. The organization’s huge size gives it a ton of power and has enabled it to do some really amazing work.
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I don’t know about you, but some days I feel sharper than others. Whether I’m trying to spike a volleyball or write a piece of code for this site, I have my good days and my bad days. There are a ton of factors that can affect how you perform on a given task from day to day, and many of them are hard to control. But the best way to overcome these fluctuations is to improve your overall skill through practice. This is pretty straightforward when you’re talking about specific tasks, but what if you are just aiming to improve your mental sharpness? As I’ve learned from reading Moonwalking with Einstein: The Art and Science of Remembering Everything memory is a skill that can be trained just like any other skill. That’s why I was intrigued when I saw a commercial for Lumosity. They’re a San Francisco, CA based company that has used cutting edge science to develop “the most effective online tool for cognitive enhancement.” I’m skeptical of a lot of the claims in favor of brain teaser games, but Lumosity has actually built their products based on research from top neuroscientists at places like Stanford, UCSF, Harvard, and Columbia. It’s hard to argue with that.
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One of my favorite classes at Cornell was Animal Science 290, which was better known as “Meat Science” or “Meats.” We did pretty much everything including slaughtering, butchering, curing, cooking, and eating, but, even better, we learned all about the scientific reasons for why we were doing what we did. Everything about the class was great (especially the eating), but one of the unexpected benefits was getting to interact with an entirely different group of students than I was accustomed to. A lot of the kids in the class actually grew up on real, working farms, and I don’t think that I had ever met anyone my age who grew up on a farm before Cornell. They were the kind of kids I assumed did 4-H in high school. It turns out that my view of 4-H was a bit narrow, as it’s much more than an organization for farm kids–it’s a non-profit that “empowers youth to reach their full potential, working and learning in partnership with caring adults” in all environments. 4-H is based in Chevy Chase, MD, and it’s pretty clear from their website that they’re trying to build an image that goes beyond agriculture. Still, 4-H is administered by the National Institute of Food and Agriculture of the United States Department of Agriculture and works through the Cooperative Extension of “America’s 109 land-grant universities,” so agriculture remains extremely important within the organization.
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When I was a kid I had this really cool electronics set that allowed me to build all kinds of devices just by connecting different wires to each other. It looked kind of like this. A friend and I even built our own radio transmitter and were able to transmit music about 20 feet to my mom’s car. It totally blew our 10-year old minds. Unfortunately, neither of us had any idea how it worked. littleBits is a New York, NY based company that has more than one-upped the electronic playground. They have developed “a growing library of pre-assembled circuits that snap together with tiny magnets.” Not only do littleBits look super cool, but they should be pretty intuitive considering that each piece has a unique electronic function. I think it would be hard to play with them and not understand how they’re working.
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When I was a kid, there were two kinds of visits to the doctor’s office: ones where I had to get a shot and ones where I didn’t. Children will never be able to understand how lucky they are to have the opportunity to get poked in the arm with a needle so that they can be vaccinated. Tomorrow’s kids will be even luckier to get poked if Liquidia Technologies keeps innovating. They’re a Research Triangle Park, NC based company that is “developing engineered particle-based vaccines and therapeutics that have the potential to dramatically improve the quality of human life.” Liquidia Technologies was founded in 2004 based on discoveries made by a Professor Joseph DeSimone of UNC, and since then they’ve raised a ton of financing.
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When I was a kid, I had my own chemistry set. It was pretty cool–I could do things like change the color of a liquid by mixing a few different powders. Ok, so it wasn’t that exciting, especially after I learned that my Dad would make his own gunpowder and blow stuff up when he was a kid. After having a watered down chemistry set as a kid, I ended up having a completely inept chemistry teacher in high school. It should be no surprise that my interest in chemistry fizzled out, but if I wanted to get the reaction going again, I might look to the Chemical Heritage Foundation. They’re a Philadelphia, PA based non-profit organization that “fosters an understanding of chemistry’s impact on society” by “inspiring a passion for chemistry; highlighting chemistry’s role in meeting current social challenges; and preserving the story of chemistry and its technologies and industries across centuries.”
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Columbus Day isn’t much of a holiday anymore–it’s become yet another regular work and school day for many. It makes sense considering Christopher Columbus wasn’t really the guy that my 1st grade teacher taught me that he was. Still, I’m amazed by the feats of guys like Columbus (which is why I’ve written about Garmin and Facet Technology on past Columbus Days). Getting in a boat with an uncertain route to a far away destination still seems crazy to me, and these guys did it in a time when navigation equipment was quite basic. Their minds would be blown if they knew what kind of information the National Geospatial-Intelligence Agency (formerly the National Imagery and Mapping Agency) has. The agency is headquartered in Springfield, VA and has major facilities in St. Louis, MO (I learned about them from one of my awesome interns whose boyfriend works for the NGA). They are part of the Department of Defense, and they are tasked with providing “timely, relevant, and accurate geospatial intelligence in support of national security.”
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I lived in the Northeast for most of my life, and now that I’m in the Midwest I miss out on the fun of repeated blizzards, an earthquake, and a hurricane. Ok, natural disasters usually aren’t fun, but I can’t help but be amazed by how powerful nature can be. I’m sure a lot of you will never read this (or read it late) since there are 4 million people without power because of Hurricane Irene, but that’s not going to stop us from taking a look at the University Corporation for Atmospheric Research. They are “a non-profit consortium of more than 75 universities offering Ph.D.s in the atmospheric and related sciences.” UCAR is based in Boulder, CO and they also work with the National Science Foundation to run the National Center for Atmospheric Research.
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The idea of having my genome sequenced kind of freaks me out. I’m certainly warming to it, but I don’t like the idea of finding out about a deep, dark family secret or the fact that I’m predisposed to some kind of cancer from a DNA test. I know it’s irrational, and I know that I’ll overcome it eventually. I fully expect that within 20 years every child born in the U.S. will have his or her genome sequenced at birth. So maybe I should just the bite the bullet and get my genome sequenced. But if I’m going to do that, I need your help. The other day I came across a post about Palo Alto, CA based DNAnexus on Hacker News (an awesome site for programmers and people interested in startups). The post was focused on the company’s referral program that offers $20,000 and a full genome sequencing to anyone who refers a software engineer that they hire. That clearly caught my attention (I am trying to run a business here), but, more importantly, it introduced me to what DNAnexus is doing. A single genome contains over 100 gigabytes of data. Storing and analyzing this data requires some serious hardware, especially if you want to do it on a large scale. DNAnexus is an “early-stage software technology company that aims to become the data platform of the genome era.”
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Everything that I learned about DNA I learned from the O.J. Simpson trial and Jurassic Park. That’s not entirely true, but it’s scarily close. DNA analysis seemed so futuristic back then, but now it’s an everyday type thing. Still, there continues to be a ton of innovation in the world of molecular DNA diagnostics, and one of the leaders is OpGen, which used to be headquartered in Madison, WI, but is now located in Gaithersburg, MD. OpGen’s business is based on “a unique and powerful Optical Mapping Technology that rapidly generates high-resolution, ordered, whole genome restriction maps from single DNA molecules.” I’d explain that to you if I could, but I think you’re better off reading OpGen’s explanation of Optical Mapping.
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You wouldn’t think that I’m actually happy when people unsubscribe from this list, but if it means that they landed a job or internship, then I’m as pleased as can be. I always try to find out where former subscribers go intern somewhere so that I can tell you about opportunities at those places (e-mail me at willy@onedayonejob.com if you have a recommendation). One reader e-mailed me and told me that she went to work at the Center for Science in the Public Interest, which is a non-profit organization that acts “as the organized voice of the American public on nutrition, food safety, health and other issues.” They’re based in Washington, DC, and they’ve been acting in the public interest since 1971. The organization’s main goals are to “educate the public, advocate government policies that are consistent with scientific evidence on health and environmental issues, and counter industry’s powerful influence on public opinion and public policies.” Most of us forget how important of an issue food actually is, but it’s a major public health issue that is only getting worse.
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I was a senior in high school on September 11, 2001. We were told what had happened during our morning announcements period, and a few of who had free periods after went to the beach across the street from our school’s campus. We knew that on a clear day you could usually see the Twin Towers from there, but all we could see was a plume of smoke. We listened on the radio and heard reports of the towers falling and rumors of other attacks in the works. I was deeply affected by what happened that day, and since then I have been waiting for our country to bring Osama bin Laden to justice. Yesterday, a group of NAVY SEALs did just that under the command of the Central Intelligence Agency, which is based in Washington, DC but operates all over the world. I am extremely grateful to all of those who were involved–especially for those who risked their lives to make us safer. It’s a reminder of how important it is for our government agencies to have top talent working for them. WIthout great people working at the CIA and in our armed forces, bin Laden would still be at large.
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I’m in St. Louis for the weekend, mostly to watch my girlfriend’s little sister’s volleyball tournament, but I’m looking for other cool things to do since it’s my first time here. Yesterday I got to visit the Saint Louis Zoo, which is fantastic. (And I promise I didn’t act like this kid.) I got to see monkeys, giraffes, zebras, lions, penguins, gorillas, elephants, somali wild asses, and a whole range of other animals that I’d never even heard of before. I even got to see the mountain nyala that makes an appearance in the zoo’s logo. I was really impressed with the Saint Louis Zoo—it has a wonderful layout and an amazing collection of animals. The best part, though, was that we got to see feeding time for the grizzly bears. It may sound barbaric, but it was nothing of the sort. We watched as two of the laziest bears that I’ve ever seen would catch oranges in their mouths and then suck out the meat while leaving behind the rind. What made the experience even better was that it was free. Saint Louis Zoo is a “free zoo,” so all you have to pay for is parking.
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The Washington Media Scholars Program runs a case competition for college students every year. Participating can get you a scholarship, a trip to DC, networking opportunities, and even extra credit for a class. Learn more here.
Everything that I know about aerodynamics I learned from MythBusters. Ok, that’s not completely true–AP Physics taught me a little bit too, but MythBusters does a remarkable job of explaining how different objects (from bullets to cars) react to the drag forces of air and water. Today I found a company that puts MythBusters to shame, at least when it comes to aerodynamics (but definitely not when it comes to explosions). Their name is Exa, and they’re a Burlington, MA based company that “develops, markets, and supports simulation software for the fluids engineering marketplace along with a full suite of engineering consulting services.” They typically work with companies in the “automotive, aerospace, architectural, environmental, electronic, and heavy equipment industries,” so I’m sure that you can imagine what kind of cool projects they’ve been involved with. Think optimizing the USA 4-man bobsled that won the Olympic Gold Medal or providing simulations for a Discovery Channel TV show called Ultimate Car Build-Off (ok, it’s not MythBusters).
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In just the past year and a half, I’ve lost two important people in my life to cancer. Chances are that you’ve been similarly affected by the disease considering that 1 in 4 deaths in this country are caused by cancer and that there were more than 1.5 million new cancer cases last year. The numbers sound grim, but every year we’re getting better and better at treating cancer. One of the major trends that I keep hearing about is that doctors are starting to see cancers as individual diseases instead of as one disease that affects many areas of the body. Precision Therapeutics is a Pittsburgh, PA based company that is taking this idea once step further. They believe that cancer should be treated at an individual level. In other words, they see every single case of cancer as potentially unique, and they want to help doctors and patients find the best way to treat it.
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The other day I read a fascinating article about a Canadian guy who figured out how to determine whether scratch-off lottery tickets would be winners… without scratching them off. He decided not to take advantage of his discovery, because he realized he made more money as a statistician then he would have made taking advantage of the flaw. When he tried to tell the Ontario Lottery and Gaming Corporation, they thought he was some crackpot and ignored him. Finally, he got their attention when he sent them 20 tickets with predictions of their outcomes—he was right on 19 out of 20 of them. The article mentioned the names of a few U.S. based companies that work in the scratch-off lottery games, and I instantly wondered whether they had any internship. One of those companies is Scientific Games, which is headquartered in New York, NY but appears to be operationally based in Alpharetta, GA. Lotteries in the U.S. are a $50 billion market, and Scientific Games is “the primary instant ticket provider for 8 of the top 10 U.S. lotteries.” It may not seem as though there is a lot of room for innovation in lottery games, but Scientific Games has consistently proved otherwise.
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Generally, we as a society trust scientists. We see them as unbiased and smarter than us, so we look to them when we need answers to complex questions. However, we often don’t respond to those answers as well as we should. Part of the problem is that science is ever changing—what was thought to be true last year has now been updated (or reversed) based on new research. When you have different experts on the same subject saying different things, you as a layperson don’t know whom to listen to. But when scientists come together on an issue and vocally push for action, it’s time to listen. The Union of Concerned Scientists is a non-profit organization that was founded in 1969 “by a group of scientists and students at the Massachusetts Institute of Technology to protest the militarization of scientific research and promote science in the public interest.” They’re based in Cambridge, MA, and they are “now an alliance of more than 250,000 citizens and scientists” with members “from all walks of life: parents and businesspeople, biologists and physicists, teachers and students.”
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Today marks the end of vacation for a lot of people. Tomorrow morning’s blaring alarm will mean back to work or back to school, and the great feeling of the New Year will start to wear off. I have a couple of days left, but I’m not too excited to go back to Chicago’s predicted 19-degree weather on Tuesday night. But what if going back to work or school meant returning to an island in the Bahamas? That would change some attitudes, which is why you should envy the teachers and students at The Island School on Cape Eleuthra. The Island School calls itself “a mind, body, and spirit journey that takes students away from traditional high school curriculum and invites them to confront authentic challenges” where “classes are designed to allow first-hand engagement with the people and environment of The Bahamas.” It’s most definitely not a vacation, but it’s education in a far more welcoming environment.
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Ten days ago we took a look at Rodale Institute, a non-profit that is “dedicated to pioneering organic farming through research and outreach.” We talked about how industrial farming has led to amazing boosts in productivity, but it’s also created a lot of problems. Marrone Bio Innovations is a Davis, CA based company that is taking a natural approach to one specific area of agriculture: pest control. They’re aiming to be “the world leader in natural product innovation” by making “natural, effective, safe, environmentally friendly products the mainstream future of pest management.” Usually you don’t hear organic and pesticide in the same sentence, but Marrone Bio Innovations’ business is predicated on bringing the two together.
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You can sell anything to new parents. They want to create a perfect world for their new baby, so they often tend to go overboard on things like strollers, cribs, mobiles, and clothes. Recently, an expensive new option for parents-to-be has come to market. It seems a little out there at first, but it has the potential to be the most valuable purchase/investment that a parent could make. It’s having your child’s stem cells banked at birth by freezing the blood from the umbilical cord. The mention of stem cells often creates a lot of controversy, but that’s almost always directed at embryonic stem cell research. There are plenty of other ways to procure stem cells—and umbilical cord blood is one of the best, especially for individual medical use. Stem cell therapies are still pretty uncommon, but the hope is that future therapies will be available to those who have had their stem cells banked—and there’s already a long list of diseases that have been treated with stem cells from cord blood. Cord Blood Registry in San Bruno, CA is the world’s “largest and most experience cord blood bank” having “already saved cord blood for more than 325,000 newborns.” Banking cord blood may not be all that common yet, but if you’re going to do it, it looks like Cord Blood Registry is the place to go.
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Just two weeks ago we were talking about market failures and externalities when we looked at The Institute for Market Transformation. Today we’re going to look at an organization that focuses on a single issue that is dominated by externalities. Antibiotics are truly wonder drugs. They can cure all kinds of ailments. One of their few downfalls is that the more that they’re used, the less effective they become. Now, this isn’t an individual drug resistance, but a worldwide one. If I use an antibiotic today, it may not work as well for you next year. Unfortunately, individual incentives for both doctors and patients lead to antibiotic overuse. The Alliance for the Prudent Use of Antibiotics is a Boston, MA based non-profit organization that does exactly what its name says. Their “specialized staff provides field consultations and lend specialized expertise to guide policy makers, provider organizations, and other stakeholders seeking to improve antimicrobial supply, use, and management decisions.”
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I don’t think there’s a gamer out there who hasn’t been hounded by a parent to turn off the video gaming system of choice and do his or her homework. I’m sure some gamers get the last laugh when they start a high-paying career in game development, but most parents still fail to see the educational value of video games. Maybe if they hear about GameDesk, they’ll change their tune. It’s a Los Angeles, CA based “non-profit research and outreach organization designed to help close the achievement gap and improve academic outcomes by reshaping models for learning through game-play and game development.” Yes, it may be hard to believe for some, but critical math, english, and science concepts can be tough through games.
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video games,
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While on a fishing trip last month, I met a guy who was telling me about his daughter’s coursework in forensics. He mentioned that her college’s program has its own house for practicing crime scene investigation. Apparently, it’s filled with all kind of carnage—you know, bullet holes, blood stains, and other—ahem—bodily fluids. I told the guy that I didn’t understand how this house was any different from most college housing after a good weekend, but he didn’t seem to appreciate the humor. My point is that the area of forensics is growing, and Kalamazoo, MI based Forensic Fluids Laboratories is a perfect example of this. They’re an Inc. 500 company with 1,680.7% three-year revenue growth and $2.8 million in annual revenue. Forensic Fluids Laboratories specializes in testing oral fluids—in other words, spit—with a heavy emphasis on drug testing.
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biology,
chemistry,
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laboratory,
medicine,
Michigan,
science,
toxicology
When I was in Kindergarten, I was given a tree seedling in a half milk carton. I was supposed to bring it home and plant it. I’m sure there was some other lesson that came with the seedling, but all I can remember is having my own tree and thinking it was cool. I went home and planted the tree in a marginal spot where it took way too long to grow. The tree even made the move when my parents bought a new house, but it only lasted a few months in its new spot. This tree was obviously part of my “green education,” and that was back in the early 90s. Obviously, the need for environmental education continues to grow, and the Green Education Foundation in Walpole, MA is aiming to fill the growing need. They are a “non-profit organization that provides environmental education resources for Pre K-12 classrooms and youth groups nationwide.” I don’t know if seedlings in milk cartons is still in, but I bet the Green Education Foundation has much more innovative ways of teaching now.
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conservation,
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education,
environmental,
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